Research Seminar
From metabolomics data to biological networksAge SmildeUniversity of Amsterdam and TNO Systems Biology | |
| Abstract: | Systems biology is the study of biology as an integrated system of genetic-, protein-, metabolite-, cellular- and pathway events that are in flux and interdependent. Due to the availability of advanced instrumentation it is possible to generate very complex data sets and a systems biology approach becomes a possibility. A part of systems biology is metabolomics. The amount of data generated in metabolomics studies is huge and the data can be very complicated. Depending on the experimental design used for the metabolomics experiments, the data contain information about underlying biological networks (e.g., a metabolic network). Finding networks in metabolomics data is a challenging and non-trivial task. Yet, it is possible to infer network properties from metabolomics data. Such network properties are able to pinpoint, e.g, the differences between healthy and diseased individuals. The general idea of network inference from metabolomics data will be outlined. Some first results and examples will be given for real-life metabolomics data in different areas of biology. |
| Date: | Tue Mar 18, 12:15 pm - 1:15 pm |
| Place: | room 02.51 (Department of Psychology, Tiensestraat 102, 3000 Leuven) |